THE LEEHICAM LAB.

Research

THE LEEHICAM LAB.

Research

Human Microbiome

OVERVIEW

Humans engage in a co-evolutionary relationship with trillions of microorganisms, a dynamic increasingly recognized as pivotal for human health. Notably, disruptions in the composition or function of the gut microbiome, referred to as dysbiosis, exert adverse effects on health. Our laboratory focuses predominantly on investigating ulcerative colitis (UC) to identify potential biomarkers for diagnosis, prevention, and prognosis enhancement. Fecal Microbiota Transplantation (FMT) emerges as a clinical therapeutic for UC, and our research comprehensively delves into the impact of FMT on the gut microbiome, seeking to discern microbial composite materials with potential applications in the future care of UC patients.

RESEARCH TOPICS

- FACS-based high-throughput screening of potential therapeutic microbes- Genome-based functional characterization of human microbiota- Unveiling the mechanism of host-microbiota interaction via microbial metabolites